It's the end of an era as this is the last part of Paul Rainey's long comic book story. Go buy it here, if you are not already reading it, why not?
I read the whole thing through after searching around on my shelves for an hour to find all the issues and then read the final issue last night. I can't say much about it as I don't want to give away anything but it's great. Lots of questions are answered and it hangs together really well as a massive long story. I recommend catching up on the earlier ones before you read it so you can notice all the subtle things.